Renal catabolism of advanced glycation end products: The fate of pentosidine
نویسندگان
چکیده
منابع مشابه
Advanced glycation end products
Aging is the progressive accumulation of damage to an organism over time leading to disease and death. Aging research has been very intensive in the last years aiming at characterizing the pathophysiology of aging and finding possibilities to fight age-related diseases. Various theories of aging have been proposed. In the last years advanced glycation end products (AGEs) have received particula...
متن کاملAdvanced glycation end-products pentosidine and N-carboxymethyllysine are elevated in serum of patients with osteoporosis
Objective. To investigate serum levels of the advanced glycation end-products (AGEs) pentosidine and N-carboxymethyllysine (CML) in patients classified into different osteoporosis subgroups according to histomorphometric data. Method. Serum samples were obtained from 116 osteoporotic patients (34 men, 82 women) classified by bone histomorphometry into subgroups with high turnover (HTO, n1⁄4 32)...
متن کاملAdvanced glycation end products, soluble receptor for advanced glycation end products, and risk of colorectal cancer.
BACKGROUND Advanced glycation end products (AGE) accumulate in human tissue proteins during aging, particularly under hyperglycemia conditions. AGEs induce oxidative stress and inflammation via the receptor for AGEs (RAGE) and soluble RAGE (sRAGE) can neutralize the effects mediated by RAGE-ligand engagement. METHODS We examined the association between N(ε)-(carboxymethyl)lysine (CML), a prom...
متن کاملAdvanced glycation end products and the kidney
Bohlender, Jürgen M., Sybille Franke, Günter Stein, and Gunter Wolf. Advanced glycation end products and the kidney. Am J Physiol Renal Physiol 289: F645–F659, 2005; doi:10.1152/ajprenal.00398.2004.—Advanced glycation end products (AGEs) are a heterogeneous group of protein and lipids to which sugar residues are covalently bound. AGE formation is increased in situations with hyperglycemia (e.g....
متن کاملSalvia reuterana Extract Prevents Formation of Advanced Glycation End Products: An In Vitro Study
In this study, we examined the antioxidant activities of methanolic extract of three endemic species of Salvia from Iran (S. lachno...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Kidney International
سال: 1998
ISSN: 0085-2538
DOI: 10.1046/j.1523-1755.1998.00756.x